It may be within the scope of practice of the competent and appropriately trained registered nurse to administer and “read” the tuberculosis (TB) skin test under the direction of an authorized health care practitioner. A prescription or order from an authorized provider is required as TB skin test formulations are a legend drug. Standing orders may be used. The registered nurse should use the Scope of Practice Decision Tree to determine if this activity is within the regulatory and individual scope of practice. The order may be made using a standing order. The prescriber or the registered nurse does not need to be on the premises when the registered nurse is administering medications. The registered nurse should communicate with the medical provider as appropriate or follow standing orders as appropriate for additional follow-up and referral. The Nursing Care Quality Assurance Commission recommends the registered nurse follow the Washington State Tuberculosis Laws and Guidelines and the Centers for Disease Control Guidelines for TB Screening and Follow-Up. Refer to the Standing Order Advisory Opinion for more information on use of standing orders.