Can the registered nurse perform bladder instillation therapy?

It is within the scope of practice of an appropriately prepared and competent registered nurse to perform bladder instillation therapy under the direction of an authorized health care practitioner, following clinical practice standards. Examples include instillation of dimethyl sulfoxide (DSMO), chemotherapy (e.g. Mitomycin C), and Bacillus Calmette-Guérin (immunotherapy) drugs. There must be an order from an authorized provider. The registered nurse should use the Scope of Practice Decision Tree to determine if these activities are within the nurse’s legal and individual scope of practice.